Epidemiology and etiopathogenesis of multiple myeloma and monoclonal gammapathy of undetermined significance
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منابع مشابه
Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma.
Monoclonal gammopathy of undetermined significance (MGUS) is characterized by the presence of a serum monoclonal (M) protein level less than 3 g/dL, less than 10% clonal plasma cells in the bone marrow, and the absence of hypercalcemia, renal insufficiency, anemia, or bone lesions attributable to a clonal plasma cell disorder. Patients may be tested for a monoclonal gammopathy by serum protein ...
متن کاملFamilial monoclonal gammopathy of undetermined significance and multiple myeloma: epidemiology, risk factors, and biological characteristics.
Monoclonal gammopathy of undetermined significance (MGUS), a precursor to multiple myeloma (MM), is one of the most common premalignant conditions in the general population. The cause of MGUS is largely unknown. Recent studies show that there is an increased prevalence of MGUS in blood relatives of persons with lymphoproliferative and plasma cell proliferative disorders, suggesting presence of ...
متن کاملGammopathy of Undetermined Significance to Multiple Myeloma
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متن کاملClinical , Morphological , and Cell Kinetic Differences Among Multiple Myeloma , Monoclonal Gammopathy of Undetermined Significance , and Smoldering Multiple Myeloma
We reviewed the clinical and morphological findings in 43 cases of monoclonal gammopathy of undetermined significance (MGUS). 9 of smoldering multiple myeloma (5MM). and 23 of overt multiple myeloma (MM). In all cases. the patients physicians had requested a bone marrow examination because of the possibility of MM. In all 75 cases. 3H-thymidine labeling indices were performed. The plasma cell l...
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ژورنال
عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej
سال: 2018
ISSN: 0032-5449,1732-2693
DOI: 10.5604/01.3001.0012.7296